The Value of Serum FSH and LH in the Early Detection of Ectopic Pregnancy
Abstract
ABSTRACT
Background: Ectopic pregnancies remain an important cause of maternal morbidity and
mortality worldwide and represent the second most common cause of maternal death in
the first trimester of pregnancy.
Objectives: To determine whether serum reproductive hormones level provide the
clinician with valuable information about the early identification of ectopic pregnancy.
Methods: A cross-sectional study was conducted at Department of Obstetrics and
Gynecology at Al-Nou'man Teaching Hospital from the 1st of January 2013 to the 1st of
May 2015. A total number of fifty age-matched pregnant women with a serum B-HCG
concentration <2000 IU/L were enrolled, including twenty women with tubal ectopic
pregnancy and 30 women with intrauterine pregnancy. From each women enrolled in this
study, blood sample was collected for assessing serum productive hormones including BHCG,
follicular stimulating hormone (FSH) and luteinizing hormone (LH) using enzyme
linked immuno-sorbent assay (ELISA).
Results: A Significant higher mean level of FSH (3.29 ±2.82) and LH (1.83 ± 1.59) was
detected among women with tubal ectopic pregnancy than that among women with
intrauterine pregnancy (1.91 ± 1.05 for FSH and 0.91 ± 0.42 for LH).
Conclusion: Measurement of FSH and LH in this study group may help the clinician for
distinguishing women with ectopic pregnancy from those with intrauterine pregnancy,
facilitate early diagnosis to provide an appropriate patient care as well as helping to
preserve future fertility.
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