Comparison of Serum Leptin Level in Ectopic and Normal Pregnancy Miami Abdul Hassan Ali* FICOG, Hind Abdulkhliq Naser* CABOG, Ikhlas Mansour Saleh** CABOG, Ruaa Abdulelah Mohammed Hasan*** MBChB
Abstract
ABSTRACT Background: Leptin hormone has an important role in reproduction; its secretion increased during pregnancy from the first trimester and decrease after parturition. Alterations in leptin level are an indicator of cessation of pregnancy either normally at term or due to pathology.
Objective: To assess maternal serum leptin level in women with ectopic pregnancies and compare it with that of normal pregnant women.
Methods: A case-control study carried out in Al Emamin AlKadmain medical city, Department of Obstetrics and Gynaecology from the first of February 2014 to the first of January 2015. One hundred fifty pregnant females were included in this study, seventy five women with ectopic pregnancies considered as study group and seventy five women with singleton uncomplicated pregnancy considered as control group with maximum gestational age in both was eight weeks. Maternal age, gestational age, parity, body mass index and leptin levels, were recorded for both groups.
Results: The mean leptin level (ng/ml) in the study group was (15.25±2.84) while the mean leptin level (ng/ml) in the control group was (12.51±2.11), there was statistically significant difference between the two groups as P value < 0.0001. There was no statistically significant difference in maternal age, parity, body mass index in both study and control groups, but significant difference was found in gestational age between study and control groups as P value < 0.0001. There was a positive correlation between leptin level and body mass index in both the study and the control groups as r value 0.504, 0.637, respectively, with statistically significant difference as P value < 0.001 in both groups. There was no statistically significant difference between leptin level and maternal age, parity in both groups. While statistically significant difference was found between leptin level and gestational age only in control group as P value 0.018.
Conclusion: Maternal serum leptin level was higher in women with ectopic pregnancy compared to that of normal pregnancy.
Keywords: Serum Leptin, Ectopic pregnancy.
Copyright (c) 2017 Iraqi Medical Journal
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Share — copy and redistribute the material in any medium or format
Under the following terms:
-
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
-
NonCommercial — You may not use the material for commercial purposes.
-
NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
